4EYB
Crystal structure of NDM-1 bound to hydrolyzed oxacillin
Summary for 4EYB
Entry DOI | 10.2210/pdb4eyb/pdb |
Related | 3Q6X 3SPU 4EXS 4EXY 4EY2 4EYF 4EYL |
Descriptor | Beta-lactamase NDM-1, ZINC ION, (2R,4S)-2-[(R)-carboxy{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carbo xylic acid, ... (4 entities in total) |
Functional Keywords | metallo beta lactamase, antibiotic, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Klebsiella pneumoniae |
Cellular location | Periplasm : C7C422 |
Total number of polymer chains | 2 |
Total formula weight | 58220.81 |
Authors | Strynadka, N.C.J.,King, D.T. (deposition date: 2012-05-01, release date: 2012-08-15, Last modification date: 2024-02-28) |
Primary citation | King, D.T.,Worrall, L.J.,Gruninger, R.,Strynadka, N.C. New Delhi Metallo-Beta-Lactamase: Structural Insights into Beta-Lactam Recognition and Inhibition J.Am.Chem.Soc., 134:11362-11365, 2012 Cited by PubMed: 22713171DOI: 10.1021/ja303579d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.16 Å) |
Structure validation
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