4EY2
Crystal structure of NDM-1 bound to hydrolyzed methicillin
Summary for 4EY2
Entry DOI | 10.2210/pdb4ey2/pdb |
Related | 3Q6X 3SPU 4EXS 4EXY 4EYB 4EYF 4EYL |
Descriptor | Beta-lactamase NDM-1, (2R,4S)-2-{(R)-carboxy[(2,6-dimethoxybenzoyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ZINC ION, ... (4 entities in total) |
Functional Keywords | metallo-beta-lactamase, antibiotic, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Klebsiella pneumoniae |
Cellular location | Periplasm : C7C422 |
Total number of polymer chains | 2 |
Total formula weight | 58178.76 |
Authors | Strynadka, N.C.J.,King, D.T. (deposition date: 2012-05-01, release date: 2012-08-08, Last modification date: 2024-02-28) |
Primary citation | King, D.T.,Worrall, L.J.,Gruninger, R.,Strynadka, N.C. New Delhi Metallo-Beta-Lactamase: Structural Insights into Beta-Lactam Recognition and Inhibition J.Am.Chem.Soc., 134:11362-11365, 2012 Cited by PubMed: 22713171DOI: 10.1021/ja303579d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.17 Å) |
Structure validation
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