4EKD
Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C)
Summary for 4EKD
Entry DOI | 10.2210/pdb4ekd/pdb |
Related | 1AGR 2AF0 2BCJ 2V4Z 4EKC |
Descriptor | Guanine nucleotide-binding protein G(q) subunit alpha, Regulator of G-protein signaling 2, GUANOSINE-5'-DIPHOSPHATE, ... (9 entities in total) |
Functional Keywords | gtp-binding, regulator of g protein signaling, homology domain, gtpase activation, signaling protein-inhibitor complex, signaling protein/inhibitor |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 57460.50 |
Authors | Tesmer, J.J.G.,Nance, M.R. (deposition date: 2012-04-09, release date: 2013-01-30, Last modification date: 2023-09-13) |
Primary citation | Nance, M.R.,Kreutz, B.,Tesmer, V.M.,Sterne-Marr, R.,Kozasa, T.,Tesmer, J.J. Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex. Structure, 21:438-448, 2013 Cited by PubMed: 23434405DOI: 10.1016/j.str.2012.12.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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