2AF0
Structure of the Regulator of G-Protein Signaling Domain of RGS2
Summary for 2AF0
Entry DOI | 10.2210/pdb2af0/pdb |
Descriptor | Regulator of G-protein signaling 2 (2 entities in total) |
Functional Keywords | helix, structural genomics, structural genomics consortium, sgc, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane. Isoform 2: Cell membrane. Isoform 3: Cell membrane. Isoform 4: Cell membrane: P41220 |
Total number of polymer chains | 1 |
Total formula weight | 16994.15 |
Authors | Papagrigoriou, E.,Johannson, C.,Phillips, C.,Smee, C.,Elkins, J.M.,Weigelt, J.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Von Delft, F.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-25, release date: 2005-08-02, Last modification date: 2024-03-13) |
Primary citation | Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P. Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008 Cited by PubMed: 18434541DOI: 10.1073/pnas.0801508105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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