2AF0

Structure of the Regulator of G-Protein Signaling Domain of RGS2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005096	molecular_function	GTPase activator activity
A	0045744	biological_process	negative regulation of G protein-coupled receptor signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	116
Details	Domain: {"description":"RGS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00171","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	37
Details	Region: {"description":"Necessary to inhibit protein synthesis","evidences":[{"source":"PubMed","id":"19736320","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"33008920","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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