4EDF

Dimeric hUGDH, K94E

Summary for 4EDF

Entry DOI	10.2210/pdb4edf/pdb
Related	2Q3E 2QG4 3PRJ 3PTZ 3TF5
Descriptor	UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCOSE (3 entities in total)
Functional Keywords	oligomeric state, molecular switch, medium chain dehydrogenase, glucuronidation, mdr, rossmann fold, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	222640.69
Authors	Sennett, N.C.,Wood, Z.A. (deposition date: 2012-03-27, release date: 2012-11-21, Last modification date: 2023-09-13)
Primary citation	Sennett, N.C.,Kadirvelraj, R.,Wood, Z.A. Cofactor binding triggers a molecular switch to allosterically activate human UDP-{alpha}-D-glucose 6-dehydrogenase. Biochemistry, 51:9364-9374, 2012 Cited by PubMed: 23106432 DOI: 10.1021/bi301067w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.08 Å)

Structure validation