4EA4
Structure of the glycosylase domain of MBD4 bound to 5hmU-containing DNA
Summary for 4EA4
Entry DOI | 10.2210/pdb4ea4/pdb |
Related | 4E9E 4E9F 4E9G 4E9H 4EAB |
Descriptor | Methyl-CpG-binding domain protein 4, DNA (5'-D(*CP*CP*AP*GP*CP*GP*(5HU)P*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3'), ... (4 entities in total) |
Functional Keywords | hhh dna glycosylase family, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: O95243 |
Total number of polymer chains | 3 |
Total formula weight | 26073.39 |
Authors | Morera, S.,Vigouroux, A. (deposition date: 2012-03-22, release date: 2012-08-08, Last modification date: 2023-09-13) |
Primary citation | Morera, S.,Grin, I.,Vigouroux, A.,Couve, S.,Henriot, V.,Saparbaev, M.,Ishchenko, A.A. Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA. Nucleic Acids Res., 40:9917-9926, 2012 Cited by PubMed: 22848106DOI: 10.1093/nar/gks714 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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