4E9C
The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with LDPPLHSpTA phosphopeptide
Summary for 4E9C
| Entry DOI | 10.2210/pdb4e9c/pdb |
| Related | 4E67 4E9D |
| Related PRD ID | PRD_000809 |
| Descriptor | Serine/threonine-protein kinase PLK1, LDPPLHSpTA phosphopeptide, 2-(2-METHOXYETHOXY)ETHANOL, ... (5 entities in total) |
| Functional Keywords | serine/threonine kinase, transferase, phosphoprotein binding domain, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 28142.99 |
| Authors | Sledz, P.,Hyvonen, M.,Lang, S.,Stubbs, C.J.,Abell, C. (deposition date: 2012-03-21, release date: 2012-10-10, Last modification date: 2023-09-13) |
| Primary citation | Sledz, P.,Lang, S.,Stubbs, C.J.,Abell, C. High-throughput interrogation of ligand binding mode using a fluorescence-based assay. Angew. Chem. Int. Ed. Engl., 51:7680-7683, 2012 Cited by PubMed: 22730171DOI: 10.1002/anie.201202660 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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