4E9C
The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with LDPPLHSpTA phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PLK1 | polymer | 232 | 26755.5 | 1 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (human) | Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13 |
| 2 | B (B) | LDPPLHSpTA phosphopeptide | polymer | 11 | 1055.1 | 1 | BIRD (PRD_000809) | ||
| 3 | C, D (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 2 | Chemie (PG0) | |||
| 4 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 371 - 594 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 363 | - | expression tag |
| Pro 364 | - | expression tag |
| Leu 365 | - | expression tag |
| Gly 366 | - | expression tag |
| Ser 367 | - | expression tag |
| Pro 368 | - | expression tag |
| Glu 369 | - | expression tag |
| Phe 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27810.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 332.4 | |
| All* | Total formula weight | 28143.0 |
