4DYO

Crystal Structure of Human Aspartyl Aminopeptidase (DNPEP) in complex with Aspartic acid Hydroxamate

Replaces:  3L6S

Summary for 4DYO

DescriptorAspartyl aminopeptidase, ZINC ION, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsstructural genomics, structural genomics consortium, sgc, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q9ULA0
Total number of polymer chains1
Total molecular weight54421.16
Authors
Primary citation
Chaikuad, A.,Pilka, E.S.,Riso, A.D.,Delft, F.V.,Kavanagh, K.L.,Venien-Bryan, C.,Oppermann, U.,Yue, W.W.
Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family.
Bmc Struct.Biol., 12:14-14, 2012
PubMed: 22720794 (PDB entries with the same primary citation)
DOI: 10.1186/1472-6807-12-14
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.198200.5%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4dyo
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Molmil generated image of 4dyo
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Molmil generated image of 4dyo
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More Biological unit images

Molmil generated image of 4dyo
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Molmil generated image of 4dyo
rotated about x axis by 90°
Molmil generated image of 4dyo
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4dyo.pdb1.gz [1.78 MB])
Coordinate files for Biological unit (4dyo.pdb2.gz [306.34 KB])