4DU8
Crystal structure of Staphylococcus epidermidis D283A mevalonate diphosphate decarboxylase complexed with inhibitor DPGP
Summary for 4DU8
Entry DOI | 10.2210/pdb4du8/pdb |
Related | 3QT5 3QT6 3QT7 3QT8 4DPT 4DPU 4DPW 4DPX 4DPY 4DU7 |
Descriptor | Mevalonate diphosphate decarboxylase, 1-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}acetyl)-L-proline, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ghmp kinase family, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Staphylococcus epidermidis |
Total number of polymer chains | 2 |
Total formula weight | 74595.31 |
Authors | Barta, M.L.,McWhorter, W.J.,Geisbrecht, B.V. (deposition date: 2012-02-21, release date: 2012-07-11, Last modification date: 2023-09-13) |
Primary citation | Barta, M.L.,McWhorter, W.J.,Miziorko, H.M.,Geisbrecht, B.V. Structural basis for nucleotide binding and reaction catalysis in mevalonate diphosphate decarboxylase. Biochemistry, 51:5611-5621, 2012 Cited by PubMed: 22734632DOI: 10.1021/bi300591x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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