4DU8
Crystal structure of Staphylococcus epidermidis D283A mevalonate diphosphate decarboxylase complexed with inhibitor DPGP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mevalonate diphosphate decarboxylase | polymer | 332 | 36826.4 | 2 | UniProt (Q9FD73) Pfam (PF22700) Pfam (PF18376) | Staphylococcus epidermidis | |
| 2 | C, G (A, B) | 1-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}acetyl)-L-proline | non-polymer | 333.1 | 2 | Chemie (2P0) | |||
| 3 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 327 (UniProt: Q9FD73)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 283 | Asp 283 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73652.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 942.5 | |
| All* | Total formula weight | 74595.3 |
