The crystal structure of FANCM bound MHF complex

Summary for 4DRB

DescriptorCentromere protein S, Fanconi anemia group M protein, Centromere protein X, ... (4 entities in total)
Functional Keywordsdna repair, dna binding complex, histone fold, dna damage repair, dna binding, dna binding-protein binding complex, dna binding protein-protein binding complex, dna binding protein/protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q8N2Z9 Q8IYD8 A8MT69
Total number of polymer chains15
Total molecular weight192582.16
Tao, Y.,Niu, L.,Teng, M. (deposition date: 2012-02-17, release date: 2012-05-16)
Primary citation
Tao, Y.,Jin, C.,Li, X.,Qi, S.,Chu, L.,Niu, L.,Yao, X.,Teng, M.
The structure of the FANCM-MHF complex reveals physical features for functional assembly
Nat Commun, 3:782-782, 2012
PubMed: 22510687 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms1779
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25513 0.4% 9.3% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02