4DFP

Crystal structure of the large fragment of DNA Polymerase I from Thermus aqauticus in a ternary complex with 7-(aminopentinyl)-7-deaza-dGTP

Summary for 4DFP

• Entry DOI: 10.2210/pdb4dfp/pdb
• Related: 3KTQ 3LWL 3LWM 3M8S 3OJS 3OJU
• Descriptor: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), 5'-d(AAACGGCGCCGTGGTC)-3', ... (8 entities in total)
• Functional Keywords: dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus
• Total number of polymer chains: 3
• Total formula weight: 70819.88

Authors

Bergen, K.,Steck, A.,Struett, S.,Baccaro, A.,Welte, W.,Diederichs, K.,Marx, A. (deposition date: 2012-01-24, release date: 2012-05-16, Last modification date: 2023-09-13)

• Primary citation: Bergen, K.,Steck, A.L.,Strutt, S.,Baccaro, A.,Welte, W.,Diederichs, K.,Marx, A.; Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.; J.Am.Chem.Soc., 134:11840-11843, 2012; PubMed: 22475415; DOI: 10.1021/ja3017889

Experimental method

X-RAY DIFFRACTION (2 Å)