3OJU

Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing c5 modified thymidies

Summary for 3OJU

• Entry DOI: 10.2210/pdb3oju/pdb
• Related: 3LWL 3LWM 3M8R 3M8S 3OJS
• Descriptor: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (8 entities in total)
• Functional Keywords: dna polymerase, c5 modified nucleotide analogs, binding pocket, spin-labeled triphosphate, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus
• Total number of polymer chains: 3
• Total formula weight: 72386.99

Authors

Marx, A.,Diederichs, K.,Obeid, S. (deposition date: 2010-08-23, release date: 2010-12-15, Last modification date: 2023-09-06)

• Primary citation: Obeid, S.,Baccaro, A.,Welte, W.,Diederichs, K.,Marx, A.; Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase.; Proc.Natl.Acad.Sci.USA, 107:21327-21331, 2010; PubMed: 21123743; DOI: 10.1073/pnas.1013804107

Experimental method

X-RAY DIFFRACTION (2 Å)