3LWL

Structure of Klenow fragment of Taq polymerase in complex with an abasic site

Summary for 3LWL

• Entry DOI: 10.2210/pdb3lwl/pdb
• Related: 3KTQ 3LWM
• Descriptor: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3'), DNA (5'-D(*AP*AP*AP*(3DR)P*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (9 entities in total)
• Functional Keywords: dna replication, dna repair, dna polymerases, abasic sites, translesion synthesis, dna damage, dna-binding, dna-directed dna polymerase, amino acid-templating mechanism, transferase-dna complex, transferase/dna
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 3
• Total formula weight: 70899.78

Authors

Marx, A.,Diederichs, K.,Obeid, S. (deposition date: 2010-02-24, release date: 2010-05-05, Last modification date: 2023-11-01)

• Primary citation: Obeid, S.,Blatter, N.,Kranaster, R.,Schnur, A.,Diederichs, K.,Welte, W.,Marx, A.; Replication through an abasic DNA lesion: structural basis for adenine selectivity; Embo J., 29:1738-1747, 2010; PubMed: 20400942; DOI: 10.1038/emboj.2010.64

Experimental method

X-RAY DIFFRACTION (2.25 Å)