4D3C
Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68.
Summary for 4D3C
Entry DOI | 10.2210/pdb4d3c/pdb |
Descriptor | HEPATOCYTE GROWTH FACTOR, SFN68 FAB, ... (4 entities in total) |
Functional Keywords | protein binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 3 |
Total formula weight | 68447.68 |
Authors | Kang, Y.J.,Kim, K.L.,Cho, H.S.,Chung, J.H. (deposition date: 2014-10-21, release date: 2016-01-13, Last modification date: 2023-12-20) |
Primary citation | Kang, Y.J.,Kim, K.L.,Cho, H.S.,Chung, J.H. A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist. to be published, |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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