4CYM

Complex of human VARP-ANKRD1 with Rab32-GppCp

Summary for 4CYM

• Entry DOI: 10.2210/pdb4cym/pdb
• Related: 4CZ2
• Descriptor: RAS-RELATED PROTEIN RAB-32, ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (5 entities in total)
• Functional Keywords: transport protein, varp, rab-effector, rab, endosome, vesicle trafficking, melanosome biogenesis
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Mitochondrion: Q13637; Cytoplasm: Q96NW4
• Total number of polymer chains: 6
• Total formula weight: 144850.24

Authors

Perez-Dorado, I.,Schaefer, I.B.,McCoy, A.J.,Owen, D.J.,Evans, P.R. (deposition date: 2014-04-13, release date: 2014-06-04, Last modification date: 2023-12-20)

• Primary citation: Hesketh, G.G.,Perez-Dorado, I.,Jackson, L.P.,Wartosch, L.,Schefer, I.B.,Gray, S.R.,Mccoy, A.J.,Zeldin, O.B.,Garman, E.F.,Harbour, M.E.,Evans, P.R.,Seaman, M.N.,Luzio, J.P.,Owen, D.J.; Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.; Dev.Cell, 29:591-, 2014; PubMed: 24856514; DOI: 10.1016/J.DEVCEL.2014.04.010

Experimental method

X-RAY DIFFRACTION (2.8 Å)