4CYM
Complex of human VARP-ANKRD1 with Rab32-GppCp
Summary for 4CYM
Entry DOI | 10.2210/pdb4cym/pdb |
Related | 4CZ2 |
Descriptor | RAS-RELATED PROTEIN RAB-32, ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (5 entities in total) |
Functional Keywords | transport protein, varp, rab-effector, rab, endosome, vesicle trafficking, melanosome biogenesis |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Mitochondrion: Q13637 Cytoplasm: Q96NW4 |
Total number of polymer chains | 6 |
Total formula weight | 144850.24 |
Authors | Perez-Dorado, I.,Schaefer, I.B.,McCoy, A.J.,Owen, D.J.,Evans, P.R. (deposition date: 2014-04-13, release date: 2014-06-04, Last modification date: 2023-12-20) |
Primary citation | Hesketh, G.G.,Perez-Dorado, I.,Jackson, L.P.,Wartosch, L.,Schefer, I.B.,Gray, S.R.,Mccoy, A.J.,Zeldin, O.B.,Garman, E.F.,Harbour, M.E.,Evans, P.R.,Seaman, M.N.,Luzio, J.P.,Owen, D.J. Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface. Dev.Cell, 29:591-, 2014 Cited by PubMed: 24856514DOI: 10.1016/J.DEVCEL.2014.04.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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