4CYM

Complex of human VARP-ANKRD1 with Rab32-GppCp

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	RAS-RELATED PROTEIN RAB-32	polymer	230	25425.8	3	UniProt (Q13637) Pfam (PF00071)	HOMO SAPIENS (HUMAN)	RAB32
2	D, E, F (D, E, F)	ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27	polymer	203	22312.1	3	UniProt (Q96NW4) Pfam (PF12796)	HOMO SAPIENS (HUMAN)	VPS9-DOMAIN ANKYRIN REPEAT PROTEIN, VPS9 DOMAIN-CONTAINING P
3	G, I, K (A, B, C)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	3	Chemie (GCP)
4	H, J, L (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	131	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 225 (UniProt: Q13637)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Leu 85	Gln 85	engineered mutation

D, E, F: 450 - 640 (UniProt: Q96NW4)

PDB	External Database	Details
Gly 444	-	expression tag
Pro 445	-	expression tag
Leu 446	-	expression tag
Gly 447	-	expression tag
Ser 448	-	expression tag
Met 449	-	expression tag
His 641	-	expression tag
His 642	-	expression tag
His 643	-	expression tag
His 644	-	expression tag
His 645	-	expression tag
His 646	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	143213.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1636.5
All*	Total formula weight	144850.2

*Water molecules are not included.