4CYG
The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation
Summary for 4CYG
Entry DOI | 10.2210/pdb4cyg/pdb |
Related | 4CYF 4CYU |
Descriptor | PANTETHEINASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (2R)-2,4-dihydroxy-N-[(3S)-3-hydroxy-4-phenylbutyl]-3,3-dimethylbutanamide, ... (6 entities in total) |
Functional Keywords | hydrolase, inflammation, colitis, coa biosynthesis, oxidative stress |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 115205.08 |
Authors | Boersma, Y.L.,Newman, J.,Adams, T.E.,Sparrow, L.,Cowieson, N.,Lucent, D.,Krippner, G.,Bozaoglu, K.,Peat, T.S. (deposition date: 2014-04-11, release date: 2014-12-10, Last modification date: 2023-12-20) |
Primary citation | Boersma, Y.L.,Newman, J.,Adams, T.E.,Cowieson, N.,Krippner, G.,Bozaoglu, K.,Peat, T.S. The Structure of Vanin-1: A Key Enzyme Linking Metabolic Disease and Inflammation Acta Crystallogr.,Sect.D, 70:3320-, 2014 Cited by PubMed: 25478849DOI: 10.1107/S1399004714022767 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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