4CYG
The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | PANTETHEINASE | polymer | 506 | 56325.2 | 2 | UniProt (O95497) Pfam (PF00795) Pfam (PF19018) In PDB | HOMO SAPIENS (HUMAN) | PANTETHEINE HYDROLASE, TIFF66, VASCULAR NON-INFLAMMATORY MOLECULE 1, VANIN-1 |
2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | A, B | (2R)-2,4-dihydroxy-N-[(3S)-3-hydroxy-4-phenylbutyl]-3,3-dimethylbutanamide | non-polymer | 295.4 | 2 | Chemie (RRV) | |||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
5 | B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
6 | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 513 (UniProt: O95497)
PDB | External Database | Details |
---|---|---|
Ala 8 | - | expression tag |
Ser 9 | - | expression tag |
Ile 10 | - | expression tag |
Ser 11 | - | expression tag |
Ala 12 | - | expression tag |
Arg 13 | - | expression tag |
Asp 14 | - | expression tag |
Tyr 15 | - | expression tag |
Lys 16 | - | expression tag |
Asp 17 | - | expression tag |
Asp 18 | - | expression tag |
Asp 19 | - | expression tag |
Asp 20 | - | expression tag |
Lys 21 | - | expression tag |
Ile 26 | Thr 26 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 112650.4 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2130.2 | |
All* | Total formula weight | 115205.1 |