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4CLZ

Crystal structure of human soluble Adenylyl Cyclase with Inhibitor 4, 4'-Diisothiocyano-2,2'-stilbenedisulfonic acid

Summary for 4CLZ
Entry DOI10.2210/pdb4clz/pdb
Related4CLF 4CLK 4CLL 4CLP 4CLS 4CLT 4CLU 4CLW 4CLY 4CM0 4CM2
DescriptorADENYLATE CYCLASE TYPE 10, ACETATE ION, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywordslyase, nucleotide-binding
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight56530.23
Authors
Kleinboelting, S.,Weyand, M.,Steegborn, C. (deposition date: 2014-01-15, release date: 2014-03-05, Last modification date: 2023-12-20)
Primary citationKleinboelting, S.,Diaz, A.,Moniot, S.,Van Den Heuvel, J.,Weyand, M.,Levin, L.R.,Buck, J.,Steegborn, C.
Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate.
Proc.Natl.Acad.Sci.USA, 111:3727-, 2014
Cited by
PubMed: 24567411
DOI: 10.1073/PNAS.1322778111
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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