4CLS

Crystal structure of human soluble Adenylyl Cyclase with Pyrophosphate

Summary for 4CLS

Entry DOI	10.2210/pdb4cls/pdb
Related	4CLF 4CLK 4CLL 4CLP 4CLT 4CLU 4CLW 4CLY 4CLZ 4CM0 4CM2
Descriptor	ADENYLATE CYCLASE TYPE 10, MAGNESIUM ION, CHLORIDE ION, ... (8 entities in total)
Functional Keywords	lyase, nucleotide-binding
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	54780.65
Authors	Kleinboelting, S.,Weyand, M.,Steegborn, C. (deposition date: 2014-01-15, release date: 2014-03-05, Last modification date: 2023-12-20)
Primary citation	Kleinboelting, S.,Diaz, A.,Moniot, S.,Van Den Heuvel, J.,Weyand, M.,Levin, L.R.,Buck, J.,Steegborn, C. Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of its Activation Through Bicarbonate. Proc.Natl.Acad.Sci.USA, 111:3727-, 2014 Cited by PubMed: 24567411 DOI: 10.1073/PNAS.1322778111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation