4CLS
Crystal structure of human soluble Adenylyl Cyclase with Pyrophosphate
Functional Information from GO Data
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG A 1468 |
Chain | Residue |
A | ASP47 |
A | ASP99 |
A | POP1470 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 1469 |
Chain | Residue |
A | LYS95 |
A | LEU166 |
A | VAL167 |
A | HOH2076 |
site_id | AC3 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE POP A 1470 |
Chain | Residue |
A | SER49 |
A | GLY50 |
A | PHE51 |
A | THR52 |
A | ASP99 |
A | LYS144 |
A | ASN412 |
A | MG1468 |
A | HOH2033 |
A | ASP47 |
A | ILE48 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 1471 |
Chain | Residue |
A | ASP22 |
A | GLY90 |
A | HIS238 |
A | TYR239 |
A | TYR240 |
A | HOH2051 |
site_id | AC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE ACT A 1472 |
Chain | Residue |
A | PHE45 |
A | ARG176 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO A 1473 |
Chain | Residue |
A | PHE29 |
A | SER30 |
A | PRO31 |
A | ARG33 |
A | SER264 |
A | LYS267 |
A | HOH2029 |
A | HOH2100 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 1474 |
Chain | Residue |
A | LYS95 |
A | HIS164 |
A | ASN333 |
A | LYS334 |
A | VAL335 |
A | HOH2073 |
A | HOH2075 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00099 |
Chain | Residue | Details |
A | ASP47 | |
A | ILE48 | |
A | ASP99 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:24567411, ECO:0000269|PubMed:24616449, ECO:0007744|PDB:4CLL, ECO:0007744|PDB:4OYZ |
Chain | Residue | Details |
A | LYS95 | |
A | VAL167 | |
A | ARG176 | |
A | MET337 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:25040695, ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0007744|PDB:4USW |
Chain | Residue | Details |
A | LYS144 | |
A | VAL406 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0000305|PubMed:25040695 |
Chain | Residue | Details |
A | ASN412 |