4CL1
The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors
Summary for 4CL1
Entry DOI | 10.2210/pdb4cl1/pdb |
Descriptor | NON-STRUCTURAL PROTEIN 5A, ZINC ION, SULFATE ION (3 entities in total) |
Functional Keywords | viral protein |
Biological source | HEPATITIS C VIRUS (ISOLATE H77) |
Total number of polymer chains | 4 |
Total formula weight | 79680.25 |
Authors | Lambert, S.M.,Langley, D.R.,Garnett, J.A.,Angell, R.,Hedgethorne, K.,Meanwell, N.A.,Matthews, S.J. (deposition date: 2014-01-10, release date: 2014-04-02, Last modification date: 2023-12-20) |
Primary citation | Lambert, S.M.,Langley, D.R.,Garnett, J.A.,Angell, R.,Hedgethorne, K.,Meanwell, N.A.,Matthews, S.J. The Crystal Structure of Ns5A Domain 1 from Genotype 1A Reveals New Clues to the Mechanism of Action for Dimeric Hcv Inhibitors. Protein Sci., 23:723-, 2014 Cited by PubMed: 24639329DOI: 10.1002/PRO.2456 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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