4CL1

The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
B	0008270	molecular_function	zinc ion binding
C	0008270	molecular_function	zinc ion binding
D	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 199

Chain	Residue
A	CYS10
A	CYS28
A	CYS30
A	CYS51

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 199

Chain	Residue
B	CYS10
B	CYS28
B	CYS30
B	CYS51

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 199

Chain	Residue
C	CYS28
C	CYS30
C	CYS51
C	CYS10

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 199

Chain	Residue
D	CYS10
D	CYS28
D	CYS30
D	CYS51

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 200

Chain	Residue
A	ARG12
A	ARG52
A	SER56
A	THR58
C	ARG49

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