4CIM
Complex of a Bcl-w BH3 mutant with a BH3 domain
Summary for 4CIM
Entry DOI | 10.2210/pdb4cim/pdb |
Related | 4CIN |
Descriptor | BCL-2-LIKE PROTEIN 2, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | apoptosis, cell death |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Mitochondrion membrane ; Peripheral membrane protein : Q92843 Q92843 |
Total number of polymer chains | 4 |
Total formula weight | 41269.99 |
Authors | Colman, P.M.,Lee, E.F.,Fairlie, W.D. (deposition date: 2013-12-12, release date: 2014-11-12, Last modification date: 2023-12-20) |
Primary citation | Lee, E.F.,Dewson, G.,Evangelista, M.,Pettikiriarachchi, A.,Zhu, H.,Colman, P.M.,Fairlie, W.D. The Functional Differences of Pro-Survival and Pro-Apoptotic B Cell Lymphoma 2 (Bcl-2) Proteins Depend on Structural Differences in Their Bcl-2 Homology 3 (Bh3) Domains J.Biol.Chem., 289:36001-, 2014 Cited by PubMed: 25371206DOI: 10.1074/JBC.M114.610758 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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