4CAK
Three-dimensional reconstruction of intact human integrin alphaIIbbeta3 in a phospholipid bilayer nanodisc
Summary for 4CAK
Entry DOI | 10.2210/pdb4cak/pdb |
EMDB information | 2281 |
Descriptor | Integrin alpha-IIb, Integrin beta-3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | cell adhesion, integrin, single particle reconstruction |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 184314.93 |
Authors | Choi, W.S.,Rice, W.J.,Stokes, D.L.,Coller, B.S. (deposition date: 2013-10-08, release date: 2013-10-30, Last modification date: 2020-07-29) |
Primary citation | Choi, W.S.,Rice, W.J.,Stokes, D.L.,Coller, B.S. Three-Dimensional Reconstruction of Intact Human Integrin Alphaiibbeta3; New Implications for Activation-Dependent Ligand Binding. Blood, 122:4165-, 2013 Cited by PubMed: 24136164DOI: 10.1182/BLOOD-2013-04-499194 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (20.5 Å) |
Structure validation
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