4CAD

Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1

Summary for 4CAD

Entry DOI	10.2210/pdb4cad/pdb
Descriptor	ANTIBODY FAB FRAGMENT LIGHT CHAIN, ANTIBODY FAB FRAGMENT HEAVY CHAIN, RAS AND A-FACTOR CONVERTING ENZYME 1, RCE1, ... (6 entities in total)
Functional Keywords	protein binding, integral membrane protease, monoclonal antibody fab fragment
Biological source	METHANOCOCCUS MARIPALUDIS More
Total number of polymer chains	12
Total formula weight	318563.18
Authors	Kulkarni, K.,Manolaridis, I.,Dodd, R.B.,Cronin, N.,Ogasawara, S.,Iwata, S.,Barford, D. (deposition date: 2013-10-08, release date: 2013-11-27, Last modification date: 2023-12-20)
Primary citation	Manolaridis, I.,Kulkarni, K.,Dodd, R.B.,Ogasawara, S.,Zhang, Z.,Bineva, G.,O'Reilly, N.,Hanrahan, S.J.,Thompson, A.J.,Cronin, N.,Iwata, S.,Barford, D. Mechanism of Farnesylated Caax Protein Processing by the Intramembrane Protease Rce1 Nature, 504:301-, 2013 Cited by PubMed: 24291792 DOI: 10.1038/NATURE12754 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation