4C68

Plasmodium vivax N-myristoyltransferase in complex with a peptidomimetic inhibitor

Summary for 4C68

• Entry DOI: 10.2210/pdb4c68/pdb
• Related: 4C7H 4C7I
• Descriptor: GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, FORMIC ACID, DIMETHYL SULFOXIDE, ... (9 entities in total)
• Functional Keywords: transferase, myristoylation, malaria
• Biological source: PLASMODIUM VIVAX
• Total number of polymer chains: 3
• Total formula weight: 139621.37

Authors

Olaleye, T.O.,Brannigan, J.A.,Goncalves, V.,Roberts, S.M.,Leatherbarrow, R.J.,Wilkinson, A.J.,Tate, E.W. (deposition date: 2013-09-17, release date: 2014-09-24, Last modification date: 2024-05-08)

• Primary citation: Olaleye, T.O.,Brannigan, J.A.,Roberts, S.M.,Leatherbarrow, R.J.,Wilkinson, A.J.,Tate, E.W.; Peptidomimetic Inhibitors of N-Myristoyltransferase from Human Malaria and Leishmaniasis Parasites.; Org.Biomol.Chem., 12:8132-, 2014; PubMed: 25230674; DOI: 10.1039/C4OB01669F

Experimental method

X-RAY DIFFRACTION (1.38 Å)