4C7H

Leismania major N-myristoyltransferase in complex with a peptidomimetic (-NH2) molecule

Summary for 4C7H

Entry DOI	10.2210/pdb4c7h/pdb
Related	4C68 4C7I
Descriptor	GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, N-(10-aminodecanoyl)-L-seryl-N-(2-cyclohexylethyl)-L-lysinamide, ... (8 entities in total)
Functional Keywords	transferase, myristoylation
Biological source	LEISHMANIA MAJOR
Total number of polymer chains	1
Total formula weight	50669.96
Authors	Olaleye, T.O.,Brannigan, J.A.,Goncalves, V.,Roberts, S.M.,Leatherbarrow, R.J.,Wilkinson, A.J.,Tate, E.W. (deposition date: 2013-09-20, release date: 2014-09-24, Last modification date: 2014-10-08)
Primary citation	Olaleye, T.O.,Brannigan, J.A.,Roberts, S.M.,Leatherbarrow, R.J.,Wilkinson, A.J.,Tate, E.W. Peptidomimetic Inhibitors of N-Myristoyltransferase from Human Malaria and Leishmaniasis Parasites. Org.Biomol.Chem., 12:8132-, 2014 Cited by PubMed: 25230674 DOI: 10.1039/C4OB01669F PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation