4BWS
Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.
Summary for 4BWS
Entry DOI | 10.2210/pdb4bws/pdb |
Related | 4BWQ |
Descriptor | THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN 1, CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2, ... (4 entities in total) |
Functional Keywords | transcription, neurodegenerative disorders |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P83876 O60828 Cytoplasm: O95400 |
Total number of polymer chains | 6 |
Total formula weight | 58203.60 |
Authors | Mizuguchi, M.,Obita, T.,Serita, T.,Kojima, R.,Morimoto, T.,Nabeshima, Y.,Okazawa, H. (deposition date: 2013-07-04, release date: 2014-04-30, Last modification date: 2023-12-20) |
Primary citation | Mizuguchi, M.,Obita, T.,Serita, T.,Kojima, R.,Nabeshima, Y.,Okazawa, H. Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5:3822-, 2014 Cited by PubMed: 24781215DOI: 10.1038/NCOMMS4822 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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