4BWS

Crystal structure of the heterotrimer of PQBP1, U5-15kD and U5-52kD.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	THIOREDOXIN-LIKE PROTEIN 4A	polymer	142	16743.2	2	UniProt (P83876) Pfam (PF02966)	HOMO SAPIENS (HUMAN)	DIM1 PROTEIN HOMOLOG, SPLICEOSOMAL U5 SNRNP-SPECIFIC 15 KDA PROTEIN, THIOREDOXIN-LIKE U5 SNRNP PROTEIN U5-15KD, U5-15KD
2	B, E (B, E)	POLYGLUTAMINE-BINDING PROTEIN 1	polymer	37	3876.2	2	UniProt (O60828)	HOMO SAPIENS (HUMAN)	PQBP-1,38 KDA NUCLEAR PROTEIN CONTAINING A WW DOMAIN, NPW38, POLYGLUTAMINE TRACT-BINDING PROTEIN 1, PQBP-1
3	C, F (C, F)	CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2	polymer	71	8482.4	2	UniProt (O95400) Pfam (PF02213)	HOMO SAPIENS (HUMAN)	CD2 CYTOPLASMIC DOMAIN-BINDING PROTEIN 2, CD2 TAIL-BINDING PROTEIN 2, U5 SNRNP 52K PROTEIN, U5-52K, U5-52KD
4	G, H, I, J (A, C, D, F)	water	water		18.0	16	Chemie (HOH)

Sequence modifications

A, D: 4 - 137 (UniProt: P83876)

PDB	External Database	Details
Met -4	-	expression tag
Ala -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag

C, F: 280 - 341 (UniProt: O95400)

PDB	External Database	Details
Met 271	-	expression tag
Ala 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag
His 277	-	expression tag
His 278	-	expression tag
Met 279	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	58203.6
All*	Total formula weight	58203.6

*Water molecules are not included.