4BWQ

Crystal structure of U5-15kD in a complex with PQBP1

Summary for 4BWQ

• Entry DOI: 10.2210/pdb4bwq/pdb
• Related: 4BWS
• Descriptor: THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN 1 (3 entities in total)
• Functional Keywords: transcription, neurodegenerative disorders
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: P83876 O60828
• Total number of polymer chains: 8
• Total formula weight: 85397.14

Authors

Mizuguchi, M.,Obita, T.,Serita, T.,Kojima, R.,Morimoto, T.,Nabeshima, Y.,Okazawa, H. (deposition date: 2013-07-04, release date: 2014-04-30, Last modification date: 2023-12-20)

• Primary citation: Mizuguchi, M.,Obita, T.,Serita, T.,Kojima, R.,Nabeshima, Y.,Okazawa, H.; Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd.; Nat.Commun., 5:3822-, 2014; PubMed: 24781215; DOI: 10.1038/NCOMMS4822

Experimental method

X-RAY DIFFRACTION (2.1 Å)