4BUR
Crystal structure of the reduced human Apoptosis inducing factor complexed with NAD
Summary for 4BUR
Entry DOI | 10.2210/pdb4bur/pdb |
Related | 4BV6 |
Descriptor | APOPTOSIS INDUCING FACTOR 1, MITOCHONDRIAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | apoptosis, mitochondria, nuclear chromatinolysis, dna-binding, flavoprotein, oxidoreductase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion intermembrane space. Isoform 3: Mitochondrion intermembrane space. Isoform 5: Cytoplasm: O95831 |
Total number of polymer chains | 4 |
Total formula weight | 231634.83 |
Authors | Martinez-Julvez, M.,Herguedas, B.,Hermoso, J.A.,Ferreira, P.,Villanueva, R.,Medina, M. (deposition date: 2013-06-23, release date: 2014-07-09, Last modification date: 2023-12-20) |
Primary citation | Ferreira, P.,Villanueva, R.,Martinez-Julvez, M.,Herguedas, B.,Marcuello, C.,Fernandez-Silva, P.,Cabon, L.,Hermoso, J.A.,Lostao, A.,Susin, S.A.,Medina, M. Structural Insights Into the Coenzyme Mediated Monomer-Dimer Transition of the Pro-Apoptotic Apoptosis Inducing Factor. Biochemistry, 53:4204-, 2014 Cited by PubMed: 24914854DOI: 10.1021/BI500343R PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.88 Å) |
Structure validation
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