4BTF
Structure of MLKL
Summary for 4BTF
Entry DOI | 10.2210/pdb4btf/pdb |
Descriptor | MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN, FORMIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | transferase, pseduokinase, necroptosis |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Total number of polymer chains | 1 |
Total formula weight | 54026.95 |
Authors | Czabotar, P.E.,Murphy, J.M. (deposition date: 2013-06-16, release date: 2013-09-18, Last modification date: 2024-05-08) |
Primary citation | Murphy, J.M.,Czabotar, P.E.,Hildebrand, J.M.,Lucet, I.S.,Zhang, J.-G.,Alvarez-Diaz, S.,Lewis, R.,Lalaoui, N.,Metcalf, D.,Webb, A.I.,Young, S.N.,Varghese, L.N.,Tannahill, G.M.,Hatchell, E.C.,Majewski, I.J.,Okamoto, T.,Dobson, R.C.J.,Hilton, D.J.,Babon, J.J.,Nicola, N.A.,Strasser, A.,Silke, J.,Alexander, W.S. The Pseudokinase Mlkl Mediates Necroptosis Via a Molecular Switch Mechanism Immunity, 39:443-, 2013 Cited by PubMed: 24012422DOI: 10.1016/J.IMMUNI.2013.06.018 PDB entries with the same primary citation |
Experimental method |
Structure validation
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