4BFW

Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1e) and phosphate

Summary for 4BFW

Entry DOI	10.2210/pdb4bfw/pdb
Related	4BFS 4BFT 4BFU 4BFV 4BFX 4BFY 4BFZ
Descriptor	PANTOTHENATE KINASE, PHOSPHATE ION, N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-[(4-fluorophenyl)methyl]-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, ... (4 entities in total)
Functional Keywords	transferase, coa pathway
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	2
Total formula weight	74382.50
Authors	Bjorkelid, C.,Bergfors, T.,Jones, T.A. (deposition date: 2013-03-22, release date: 2013-05-15, Last modification date: 2023-12-20)
Primary citation	Bjorkelid, C.,Bergfors, T.,Raichurkar, A.K.V.,Mukherjee, K.,Krishnan, M.,Bandodkar, B.,Jones, T.A. Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288:18260-, 2013 Cited by PubMed: 23661699 DOI: 10.1074/JBC.M113.476473 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation