4BC1
Structure of mouse acetylcholinesterase inhibited by CBDP (30-min soak): cresyl-saligenin-phosphoserine adduct
Summary for 4BC1
Entry DOI | 10.2210/pdb4bc1/pdb |
Related | 1C2B 1C2O 1J06 1J07 1KU6 1MAA 1MAH 1N5M 1N5R 1Q83 1Q84 2C0P 2C0Q 2H9Y 2HA0 2HA2 2HA3 2HA4 2HA5 2HA6 2HA7 2JEY 2JEZ 2JF0 2JGE 2JGF 2JGG 2JGH 2JGI 2JGJ 2JGK 2JGL 2JGM 2WHP 2WHQ 2WHR 2WLS 2WU3 2WU4 2XUD 2XUF 2XUG 2XUH 2XUI 2XUJ 2XUK 2XUO 2XUP 2XUQ 4A16 4A23 4ARA 4ARB 4B7Z 4B80 4B81 4B82 4B83 4B84 4B85 4BBZ 4BC0 |
Descriptor | ACETYLCHOLINESTERASE, O-CRESYL-SALIGENIN PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | hydrolase, butyrylcholinesterase, nerve transmission, inhibitor, alpha-beta hydrolase |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Total number of polymer chains | 4 |
Total formula weight | 243614.30 |
Authors | Carletti, E.,Colletier, J.-P.,Schopfer, L.M.,Santoni, G.,Masson, P.,Lockridge, O.,Nachon, F.,Weik, M. (deposition date: 2012-09-30, release date: 2013-02-06, Last modification date: 2023-12-20) |
Primary citation | Carletti, E.,Colletier, J.-P.,Schopfer, L.M.,Santoni, G.,Masson, P.,Lockridge, O.,Nachon, F.,Weik, M. Inhibition Pathways of the Potent Organophosphate Cbdp with Cholinesterases Revealed by X-Ray Crystallographic Snapshots and Mass Spectrometry Chem.Res.Toxicol., 26:280-, 2013 Cited by PubMed: 23339663DOI: 10.1021/TX3004505 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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