4B8L
Aurora B kinase P353G mutant
Summary for 4B8L
Entry DOI | 10.2210/pdb4b8l/pdb |
Related | 2BFX 2BFY 2VGO 2VGP 2VRX 3ZTX 4B8M |
Descriptor | AURORA KINASE B-A, INNER CENTROMERE PROTEIN A, 9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-9H-purin-6-amine (3 entities in total) |
Functional Keywords | cell cycle, cancer |
Biological source | XENOPUS LAEVIS (AFRICAN CLAWED FROG) More |
Cellular location | Nucleus: Q6DE08 Chromosome, centromere: O13024 |
Total number of polymer chains | 2 |
Total formula weight | 39183.94 |
Authors | |
Primary citation | Sessa, F.,Villa, F. Structural and Biochemical Analysis of an Aurora B Kinase Mutant Reveals a Multistep Activation Mechanism To be Published, |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report