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2BFX

Mechanism of Aurora-B activation by INCENP and inhibition by Hesperadin.

Summary for 2BFX
Entry DOI10.2210/pdb2bfx/pdb
Related2BFY
DescriptorAURORA KINASE B-A, INNER CENTROMERE PROTEIN A (3 entities in total)
Functional Keywordstransferase, kinase, mitosis, inhibition, transferase complex
Biological sourceXENOPUS LAEVIS (AFRICAN CLAWED FROG)
More
Cellular locationNucleus: Q6DE08
Chromosome, centromere: O13024
Total number of polymer chains4
Total formula weight77029.02
Authors
Sessa, F.,Mapelli, M.,Ciferri, C.,Tarricone, C.,Areces, L.B.,Schneider, T.R.,Stukenberg, P.T.,Musacchio, A. (deposition date: 2004-12-15, release date: 2005-05-03, Last modification date: 2023-12-13)
Primary citationSessa, F.,Mapelli, M.,Ciferri, C.,Tarricone, C.,Areces, L.B.,Schneider, T.R.,Stukenberg, P.T.,Musacchio, A.
Mechanism of Aurora B Activation by Incenp and Inhibition by Hesperadin
Mol.Cell, 18:379-, 2005
Cited by
PubMed: 15866179
DOI: 10.1016/J.MOLCEL.2005.03.031
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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