2BFX
Mechanism of Aurora-B activation by INCENP and inhibition by Hesperadin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AURORA KINASE B-A | polymer | 284 | 33537.9 | 2 | UniProt (Q6DE08) Pfam (PF00069) | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | LOC398457 PROTEIN, AURORA-B, AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A, XAIRK2-A, SERINE/THREONINE-PROTEIN KINASE 12-A, SERINE/THREONINE-PROTEIN KINASE AURORA-B-A, XAURORA-B |
| 2 | C, D (C, D) | INNER CENTROMERE PROTEIN A | polymer | 43 | 4976.6 | 2 | UniProt (O13024) Pfam (PF03941) | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | INCENP, XL-INCENP, XINC, XINCENP, MITOTIC PHOSPHOPROTEIN 130 |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 77029.0 | |
| All* | Total formula weight | 77029.0 |
