2BFX

Mechanism of Aurora-B activation by INCENP and inhibition by Hesperadin.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	AURORA KINASE B-A	polymer	284	33537.9	2	UniProt (Q6DE08) Pfam (PF00069) In PDB	XENOPUS LAEVIS (AFRICAN CLAWED FROG)	LOC398457 PROTEIN, AURORA-B, AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A, XAIRK2-A, SERINE/THREONINE-PROTEIN KINASE 12-A, SERINE/THREONINE-PROTEIN KINASE AURORA-B-A, XAURORA-B
2	C, D	INNER CENTROMERE PROTEIN A	polymer	43	4976.6	2	UniProt (O13024) Pfam (PF03941) In PDB	XENOPUS LAEVIS (AFRICAN CLAWED FROG)	INCENP, XL-INCENP, XINC, XINCENP, MITOTIC PHOSPHOPROTEIN 130
3		water	water		18.0	268	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77029.0
All*	Total formula weight	77029.0

*Water molecules are not included.