4B8L
Aurora B kinase P353G mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | AURORA KINASE B-A | polymer | 286 | 33604.0 | 1 | UniProt (Q6DE08) Pfam (PF00069) In PDB | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A, XAIRK2-A, SERINE/THREONINE-PROTEIN KINASE 12-A, SERINE/THREONINE-PROTEIN KINASE AURORA-B-A, XAURORA-B |
| 2 | D | INNER CENTROMERE PROTEIN A | polymer | 44 | 5073.8 | 1 | UniProt (O13024) Pfam (PF03941) In PDB | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | XL-INCENP, XINC, XINCENP, MITOTIC PHOSPHOPROTEIN 130 |
| 3 | A | 9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-9H-purin-6-amine | non-polymer | 506.2 | 1 | Chemie (A0P) |
Sequence modifications
A: 78 - 361 (UniProt: Q6DE08)
| PDB | External Database | Details |
|---|---|---|
| Ala 77 | - | expression tag |
| Gly 353 | Pro 353 | engineered mutation |
| Asp 362 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38677.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.2 | |
| All* | Total formula weight | 39183.9 |
