4AXX

The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP 3-phosphoglycerate and beryllium trifluoride

Summary for 4AXX

Entry DOI	10.2210/pdb4axx/pdb
Related	2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE
Descriptor	PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	ground state analogue, hereditary hemolytic anemia, phosphoprotein, glycolysis, transferase, phosphoryl transfer, nucleotide-binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P00558
Total number of polymer chains	1
Total formula weight	45425.67
Authors	Bowler, M.W. (deposition date: 2012-06-15, release date: 2013-06-26, Last modification date: 2024-08-21)
Primary citation	Pellegrini, E.,Juyoux, P.,von Velsen, J.,Baxter, N.J.,Dannatt, H.R.W.,Jin, Y.,Cliff, M.J.,Waltho, J.P.,Bowler, M.W. Metal fluorides-multi-functional tools for the study of phosphoryl transfer enzymes, a practical guide. Structure, 2024 Cited by PubMed: 39106858 DOI: 10.1016/j.str.2024.07.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation