4AXX

The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP 3-phosphoglycerate and beryllium trifluoride

Summary for 4AXX

• Entry DOI: 10.2210/pdb4axx/pdb
• Related: 2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 2Y3I 2YBE
• Descriptor: PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: ground state analogue, hereditary hemolytic anemia, phosphoprotein, glycolysis, transferase, phosphoryl transfer, nucleotide-binding
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: P00558
• Total number of polymer chains: 1
• Total formula weight: 45425.67

Authors

Bowler, M.W. (deposition date: 2012-06-15, release date: 2013-06-26, Last modification date: 2023-12-20)

• Primary citation: Bowler, M.W.,Cliff, M.J.,Blackburn, G.M.,Waltho, J.P.; Catalytic Activity in the Transitions State Analogue Stabilised Conformation of a Phosphoryl Transfer Enzyme; To be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)