2Y3I

The structure of the fully closed conformation of human PGK in complex with L-ADP, 3PG and the TSA aluminium tetrafluoride

Summary for 2Y3I

Entry DOI	10.2210/pdb2y3i/pdb
Related	2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8
Descriptor	PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	transferase, aids, hepatitis, cancer, l-nucleoside analogues, glycolysis
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	90706.98
Authors	Bowler, M.W.,Chaloin, L.,Lionne, C. (deposition date: 2010-12-21, release date: 2011-04-27, Last modification date: 2023-12-20)
Primary citation	Lallemand, P.,Chaloin, L.,Roy, B.,Barman, T.,Bowler, M.W.,Lionne, C. Interaction of Human 3-Phosphoglycerate Kinase with its Two Substrates: Is Substrate Antagonism a Kinetic Advantage? J.Mol.Biol., 409:742-, 2011 Cited by PubMed: 21549713 DOI: 10.1016/J.JMB.2011.04.048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation