4AVK
Structure of trigonal FimH lectin domain crystal soaked with an alpha- D-mannoside O-linked to propynyl pyridine at 2.4A resolution
Summary for 4AVK
Entry DOI | 10.2210/pdb4avk/pdb |
Related | 4ATT 4AUJ 4AUU 4AUY 4AV0 4AV4 4AV5 4AVH 4AVI 4AVJ |
Descriptor | FIMH, 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside, NICKEL (II) ION, ... (5 entities in total) |
Functional Keywords | cell adhesion, bacterial adhesin, type 1 fimbriae, urinary tract infection, variable immunoglobulin fold |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 2 |
Total formula weight | 34925.87 |
Authors | Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. (deposition date: 2012-05-26, release date: 2012-06-27, Last modification date: 2023-12-20) |
Primary citation | Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh. Biochemistry, 51:4790-, 2012 Cited by PubMed: 22657089DOI: 10.1021/BI300251R PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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