4AVJ

Structure of the FimH lectin domain in the trigonal space group, in complex with a methanol triazol ethyl phenyl alpha-D-mannoside at 2.1 A resolution

Summary for 4AVJ

• Entry DOI: 10.2210/pdb4avj/pdb
• Related: 4ATT 4AUJ 4AUU 4AUY 4AV0 4AV4 4AV5 4AVH 4AVI 4AVK
• Descriptor: FIMH, SULFATE ION, METHANOL TRIAZOL ETHYL PHENYL 1O-ALPHA-D-MANNOPYRANOSIDE, ... (5 entities in total)
• Functional Keywords: cell adhesion, bacterial adhesin, type 1 fimbriae, urinary tract infection, variable immunoglobulin fold
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 2
• Total formula weight: 34905.93

Authors

Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. (deposition date: 2012-05-26, release date: 2012-06-27, Last modification date: 2023-12-20)

• Primary citation: Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J.; The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh.; Biochemistry, 51:4790-, 2012; PubMed: 22657089; DOI: 10.1021/BI300251R

Experimental method

X-RAY DIFFRACTION (2.105 Å)