4AT3

CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH CPD5N

Summary for 4AT3

Entry DOI	10.2210/pdb4at3/pdb
Related	1HCF 1WWB 4ASZ 4AT4 4AT5 4F0I
Descriptor	BDNF/NT-3 GROWTH FACTORS RECEPTOR, (5Z)-5-(carbamoylimino)-3-[(5R)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylsulfanyl]-2,5-dihydroisothiazole-4-carboxamide (3 entities in total)
Functional Keywords	transferase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	34714.17
Authors	Bertrand, T.,Kothe, M.,Liu, J.,Dupuy, A.,Rak, A.,Berne, P.F.,Davis, S.,Gladysheva, T.,Valtre, C.,Crenne, J.Y.,Mathieu, M. (deposition date: 2012-05-03, release date: 2012-08-22, Last modification date: 2023-12-20)
Primary citation	Bertrand, T.,Kothe, M.,Liu, J.,Dupuy, A.,Rak, A.,Berne, P.F.,Davis, S.,Gladysheva, T.,Valtre, C.,Crenne, J.Y.,Mathieu, M. The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition. J.Mol.Biol., 423:439-, 2012 Cited by PubMed: 22902478 DOI: 10.1016/J.JMB.2012.08.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation