4AT3
CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH CPD5N
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BDNF/NT-3 GROWTH FACTORS RECEPTOR | polymer | 299 | 34351.7 | 1 | UniProt (Q16620) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | GP145-TRKB, TRK-B, NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 2, TRKB TYROSINE KINASE, TROPOMYOSIN-RELATED KINASE B |
| 2 | B (A) | (5Z)-5-(carbamoylimino)-3-[(5R)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylsulfanyl]-2,5-dihydroisothiazole-4-carboxamide | non-polymer | 362.5 | 1 | Chemie (LTI) | |||
| 3 | C (A) | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
A: 543 - 838 (UniProt: Q16620)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Met 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34351.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 362.5 | |
| All* | Total formula weight | 34714.2 |
