4AQL
HUMAN GUANINE DEAMINASE IN COMPLEX WITH VALACYCLOVIR
Summary for 4AQL
Entry DOI | 10.2210/pdb4aql/pdb |
Related | 2UZ9 |
Descriptor | GUANINE DEAMINASE, ZINC ION, 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate, ... (4 entities in total) |
Functional Keywords | hydrolase, purine metabolism |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 54010.30 |
Authors | Welin, M.,Egeblad, L.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nyman, T.,Persson, C.,Schuler, H.,Thorsell, A.G.,Tresaugues, L.,Weigelt, J.,Nordlund, P. (deposition date: 2012-04-18, release date: 2012-05-02, Last modification date: 2023-12-20) |
Primary citation | Egeblad, L.,Welin, M.,Flodin, S.,Graslund, S.,Wang, L.,Balzarini, J.,Eriksson, S.,Nordlund, P. Pan-Pathway Based Interaction Profiling of Fda-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism. Plos One, 7:37724-, 2012 Cited by PubMed: 22662200DOI: 10.1371/JOURNAL.PONE.0037724 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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