4AQL

HUMAN GUANINE DEAMINASE IN COMPLEX WITH VALACYCLOVIR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GUANINE DEAMINASE	polymer	476	53620.6	1	UniProt (Q9Y2T3) Pfam (PF01979)	HOMO SAPIENS (HUMAN)	GUANASE, GUANINE AMINASE, GUANINE AMINOHYDROLASE, GAH, P51-NEDASIN
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C (A)	2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate	non-polymer		324.3	1	Chemie (TXC)
4	D (A)	water	water		18.0	175	Chemie (HOH)

Sequence modifications

A: 1 - 454 (UniProt: Q9Y2T3)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53620.6
Non-Polymers*	Number of molecules	2
	Total formula weight	389.7
All*	Total formula weight	54010.3

*Water molecules are not included.